Panera Bread is one of the largest bakery-café chains in the restaurant industry with 1,423 U.S. locations and more than $3.2 billion in U.S. systemwide sales. It is owned by St. Louis, Mo.-based Panera Bread Co., a publicly traded restaurant company (Ticker: PNRA) that also owns the St. Louis Bread Co. and Paradise Bakery & Café brands.