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Tropical Smoothie Café offers a substantial menu of sandwiches, salads, wraps and smoothie options like Kale Lemonade. The entirely franchised chain grew its way into the Second 100 with a balanced mix of growth in units and estimated sales per unit.

Tropical Smoothie Cafe
Latest-Year U.S. systemwide sales: $149.6 million
Latest-Year sales growth: 13.8%
Second 100 sales rank: 191
U.S. unit count: 329 (up 7.9%)
ESPU: $471,900 (up 7%)